Product Details
Research-grade peptides with clear specifications, COA-backed quality verification, and Fahrenheit storage guidance for laboratory use.
SNAP-8 -10 MG
Overview
SNAP-8 is a synthetic octapeptide used in cosmetics to reduce wrinkles by interfering with neurotransmitter release at the muscle level.
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Description
SNAP-8 is a synthetic octapeptide used in cosmetics to reduce wrinkles by interfering with neurotransmitter release at the muscle level. It works by disrupting the SNARE complex, reducing muscle contractions that cause expression lines. Research suggests modest wrinkle reduction—up to about 30 percent after a month—but its skin penetration is limited, and most evidence comes from small cosmetic studies rather than large clinical trials.
SNAP-8 / Acetyl Octapeptide-3 Research Details
SNAP-8 (acetyl octapeptide-3) is a cosmetic-science peptide derived from SNAP-25 sequence concepts. Research and supplier literature focus on SNARE-complex interference models, topical formulation challenges, and expression-line appearance studies.
99%+ target purity or lot-specific COA value
Ac-Glu-Glu-Met-Gln-Arg-Arg-Ala-Asp-NH2
Lyophilized research material unless otherwise specified by COA
Research use only
Research Background
Synthetic octapeptide studied in cosmetic science as a SNAP-25/SNARE-complex mimetic peptide affecting neurotransmitter-release models. Key OneBio research contexts include cosmetic peptide formulation, snare-model assays, topical delivery research, and skin-appearance ingredient studies.
Specifications
| Compound | SNAP-8 / Acetyl Octapeptide-3 |
| SKU / Product | snap-8 |
| Molecular Weight | ~1075.2 g/mol |
| Formula / Classification | C41H70N16O16S |
| Database / Identity Note | PubChem CID 101388438 |
| Storage | -4°F long-term; 35-46°F short-term refrigerated; 39°F after reconstitution for up to 30 days when appropriate for the research protocol |
Quality Verification
Each batch should be reviewed against its Certificate of Analysis, including identity confirmation, purity method, mass/sequence or component confirmation, appearance, and lot-specific handling notes. Blend products should be checked against component-ratio documentation where available.
Laboratory Preparation
Prepare only inside a qualified laboratory using validated solvent choice, concentration, sterility, and storage protocols. For lyophilized peptides, use sterile deionized water or bacteriostatic water when appropriate for the research protocol, mix gently, maintain cold-chain handling, and avoid repeated freeze-thaw cycles.
Product-Specific Q&A
What is SNAP-8 / Acetyl Octapeptide-3 used for in research?
SNAP-8 / Acetyl Octapeptide-3 is used as a research material for cosmetic peptide formulation, snare-model assays, topical delivery research, and skin-appearance ingredient studies. It is not offered for diagnostic, therapeutic, clinical, veterinary, or human-use applications.
What mechanism is most relevant for SNAP-8 / Acetyl Octapeptide-3?
Synthetic octapeptide studied in cosmetic science as a SNAP-25/SNARE-complex mimetic peptide affecting neurotransmitter-release models.
How should SNAP-8 / Acetyl Octapeptide-3 identity and purity be verified?
Use the lot-specific Certificate of Analysis to confirm identity, purity, mass/sequence or component profile, and any method-specific data such as LC-MS/HPLC. Technical values on this page are research references and should be checked against the delivered lot.
What storage conditions apply to SNAP-8 / Acetyl Octapeptide-3?
-4°F long-term; 35-46°F short-term refrigerated; 39°F after reconstitution for up to 30 days when appropriate for the research protocol. Keep sealed, dry, protected from light, and avoid repeated freeze-thaw cycles after preparation.
References
- PMID 39551143: The Hsc70 system maintains the synaptic SNARE protein SNAP-25 in an assembly-competent state and delays its aggregation. The Journal of biological chemistry 2024.
- PMID 35055082: NGF Enhances CGRP Release Evoked by Capsaicin from Rat Trigeminal Neurons: Differential Inhibition by SNAP-25-Cleaving Proteases. International journal of molecular sciences 2022.
- PMID 10414292: Interactions of presynaptic Ca2+ channels and snare proteins in neurotransmitter release. Annals of the New York Academy of Sciences 1999.
Expanded Product Information
PeptideTech-style product tools added beneath the existing OneBio product layout: tabs, specifications, COA guidance, shipping/storage information, stock-solution guidance, verification notes, and FAQ.
| Product | Current product |
|---|---|
| Form | Lyophilized research material unless otherwise stated on the product label. |
| Purity / Identity | See product listing and available COA/batch documentation. |
| Storage | Long-term freezer storage around -4°F. Short-term refrigerated storage 35–46°F. Reconstituted materials should be handled under validated laboratory protocols. |
| Use Standard | Research-use only; not for human or animal administration. |
Third-party verification: Review the available Certificate of Analysis and batch documentation before use. Verify identity, purity, appearance, and lot-specific details against your lab requirements.
Are these products for research use only?
Yes. OneBio Research products are sold strictly for laboratory research and analytical testing.
Where do I find storage guidance?
Use the product label, COA, and the storage tab above. Long-term freezer storage is commonly referenced around -4°F; refrigerated short-term storage is 35–46°F.
Can I request documentation?
Yes. Use the COA/documentation request link or contact OneBio Research with the product and lot details.
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