Product Details
Research-grade peptides with clear specifications, COA-backed quality verification, and Fahrenheit storage guidance for laboratory use.
IGF-LR3 -1MG
Overview
IGF-1 LR3 is a modified version of insulin-like growth factor 1.
$65.00
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Description
IGF-1 LR3 is a modified version of insulin-like growth factor 1. By altering its structure, it binds less tightly to IGF-binding proteins, resulting in a much longer half-life in circulation. When it binds to the IGF-1 receptor, it activates signaling pathways like PI3K/AKT, which promote protein synthesis, cell growth, and muscle regeneration. As a result, it’s studied for its potential to enhance lean muscle mass, accelerate tissue repair, and improve overall anabolism in experimental models.
IGF-1 LR3 Research Details
IGF-1 LR3 is a long-arginine-3 analog of insulin-like growth factor-1. Research uses it to study IGF-1R signaling, PI3K/AKT and MAPK pathway activation, cell proliferation/differentiation, and the impact of binding-protein affinity on experimental exposure.
99%+ target purity or lot-specific COA value
83-amino-acid IGF-1 analog with N-terminal extension and R3 substitution; verify lot sequence by COA
Lyophilized research material unless otherwise specified by COA
Research use only
Research Background
Modified IGF-1 analog studied for IGF-1 receptor signaling with reduced binding to IGF-binding proteins compared with native IGF-1. Key OneBio research contexts include igf-1 receptor assays, growth-factor signaling, cell-culture proliferation models, and binding-protein interaction studies.
Specifications
| Compound | IGF-1 LR3 |
| SKU / Product | igf-lre3 |
| Molecular Weight | ~9.1 kDa |
| Formula / Classification | Protein analog; verify by COA |
| Database / Identity Note | Protein analog; verify by sequence/COA |
| Storage | -4°F long-term; 35-46°F short-term refrigerated; 39°F after reconstitution for up to 30 days when appropriate for the research protocol |
Quality Verification
Each batch should be reviewed against its Certificate of Analysis, including identity confirmation, purity method, mass/sequence or component confirmation, appearance, and lot-specific handling notes. Blend products should be checked against component-ratio documentation where available.
Laboratory Preparation
Prepare only inside a qualified laboratory using validated solvent choice, concentration, sterility, and storage protocols. For lyophilized peptides, use sterile deionized water or bacteriostatic water when appropriate for the research protocol, mix gently, maintain cold-chain handling, and avoid repeated freeze-thaw cycles.
Product-Specific Q&A
What is IGF-1 LR3 used for in research?
IGF-1 LR3 is used as a research material for igf-1 receptor assays, growth-factor signaling, cell-culture proliferation models, and binding-protein interaction studies. It is not offered for diagnostic, therapeutic, clinical, veterinary, or human-use applications.
What mechanism is most relevant for IGF-1 LR3?
Modified IGF-1 analog studied for IGF-1 receptor signaling with reduced binding to IGF-binding proteins compared with native IGF-1.
How should IGF-1 LR3 identity and purity be verified?
Use the lot-specific Certificate of Analysis to confirm identity, purity, mass/sequence or component profile, and any method-specific data such as LC-MS/HPLC. Technical values on this page are research references and should be checked against the delivered lot.
What storage conditions apply to IGF-1 LR3?
-4°F long-term; 35-46°F short-term refrigerated; 39°F after reconstitution for up to 30 days when appropriate for the research protocol. Keep sealed, dry, protected from light, and avoid repeated freeze-thaw cycles after preparation.
References
- PMID 36499281: N-Linked Glycosylation in Chinese Hamster Ovary Cells Is Critical for Insulin-like Growth Factor 1 Signaling. International journal of molecular sciences 2022.
- PMID 39679943: IGF-1 LR3 does not promote growth in late-gestation growth-restricted fetal sheep. American journal of physiology. Endocrinology and metabolism 2025.
- PMID 19633297: Potentiation of growth factor signaling by insulin-like growth factor-binding protein-3 in breast epithelial cells requires sphingosine kinase activity. The Journal of biological chemistry 2009.
Expanded Product Information
PeptideTech-style product tools added beneath the existing OneBio product layout: tabs, specifications, COA guidance, shipping/storage information, stock-solution guidance, verification notes, and FAQ.
| Product | Current product |
|---|---|
| Form | Lyophilized research material unless otherwise stated on the product label. |
| Purity / Identity | See product listing and available COA/batch documentation. |
| Storage | Long-term freezer storage around -4°F. Short-term refrigerated storage 35–46°F. Reconstituted materials should be handled under validated laboratory protocols. |
| Use Standard | Research-use only; not for human or animal administration. |
Third-party verification: Review the available Certificate of Analysis and batch documentation before use. Verify identity, purity, appearance, and lot-specific details against your lab requirements.
Are these products for research use only?
Yes. OneBio Research products are sold strictly for laboratory research and analytical testing.
Where do I find storage guidance?
Use the product label, COA, and the storage tab above. Long-term freezer storage is commonly referenced around -4°F; refrigerated short-term storage is 35–46°F.
Can I request documentation?
Yes. Use the COA/documentation request link or contact OneBio Research with the product and lot details.
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