Description
Human chorionic gonadotropin (hCG) is a glycoprotein hormone that plays a critical role in both pregnancy and male reproductive health. During pregnancy, it is produced by the placenta to maintain the corpus luteum, stimulate progesterone production, and support fetal development. In men, hCG acts similarly to luteinizing hormone by stimulating the testes to produce testosterone, making it valuable for treating male hypogonadism and preserving fertility. By activating these pathways, hCG supports hormone balance in both reproductive and broader metabolic contexts.
Human Chorionic Gonadotropin (hCG) Research Details
hCG is a heterodimeric glycoprotein hormone extensively studied in pregnancy biology, trophoblast signaling, LH receptor activation, steroidogenesis models, and reproductive endocrinology. OneBio content is framed as research-use biochemical material only.
99%+ target purity or lot-specific COA value
Glycoprotein hormone alpha/beta subunits; lot identity by COA
Lyophilized research material unless otherwise specified by COA
Research use only
Research Background
Glycoprotein hormone that activates the LH/CG receptor in reproductive endocrinology research. Key OneBio research contexts include lh/cg receptor studies, reproductive endocrinology assays, trophoblast biology, and glycoprotein hormone research.
Specifications
| Compound | Human Chorionic Gonadotropin (hCG) |
| SKU / Product | hcg3 |
| Molecular Weight | ~36.7 kDa glycoprotein (glycosylation-dependent) |
| Formula / Classification | Protein/glycoprotein; verify by COA |
| Database / Identity Note | Biologic/glycoprotein; verify by COA |
| Storage | -4°F long-term; 35-46°F short-term refrigerated; 39°F after reconstitution for up to 30 days when appropriate for the research protocol |
Quality Verification
Each batch should be reviewed against its Certificate of Analysis, including identity confirmation, purity method, mass/sequence or component confirmation, appearance, and lot-specific handling notes. Blend products should be checked against component-ratio documentation where available.
Laboratory Preparation
Prepare only inside a qualified laboratory using validated solvent choice, concentration, sterility, and storage protocols. For lyophilized peptides, use sterile deionized water or bacteriostatic water when appropriate for the research protocol, mix gently, maintain cold-chain handling, and avoid repeated freeze-thaw cycles.
Product-Specific Q&A
What is Human Chorionic Gonadotropin (hCG) used for in research?
Human Chorionic Gonadotropin (hCG) is used as a research material for lh/cg receptor studies, reproductive endocrinology assays, trophoblast biology, and glycoprotein hormone research. It is not offered for diagnostic, therapeutic, clinical, veterinary, or human-use applications.
What mechanism is most relevant for Human Chorionic Gonadotropin (hCG)?
Glycoprotein hormone that activates the LH/CG receptor in reproductive endocrinology research.
How should Human Chorionic Gonadotropin (hCG) identity and purity be verified?
Use the lot-specific Certificate of Analysis to confirm identity, purity, mass/sequence or component profile, and any method-specific data such as LC-MS/HPLC. Technical values on this page are research references and should be checked against the delivered lot.
What storage conditions apply to Human Chorionic Gonadotropin (hCG)?
-4°F long-term; 35-46°F short-term refrigerated; 39°F after reconstitution for up to 30 days when appropriate for the research protocol. Keep sealed, dry, protected from light, and avoid repeated freeze-thaw cycles after preparation.
References
- PMID 28723025: Physiology, Ovulation. PubMed-indexed source 2026.
- PMID 34552239: Structures of full-length glycoprotein hormone receptor signalling complexes. Nature 2021.
- PMID 29509368: Human Chorionic Gonadotropin: Unknown about Known. Fiziologiia cheloveka 2017.

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