CJC-1295 DAC -10MG

Description

CJC-1295 with DAC (Drug Affinity Complex) is a synthetic peptide analog of growth hormone-releasing hormone (GHRH). By binding to the GHRH receptor on pituitary somatotropes, it initiates a natural cascade of growth hormone (GH) release. What sets CJC-1295 with DAC apart is its deliberate conjugation to a drug affinity domain, which binds to serum albumin in the bloodstream. This binding greatly prolongs its half-life—unlike native GHRH, which acts in minutes—CJC-1295 with DAC maintains elevated GH levels for days, leading to pulsatile but sustained release. As a result, it increases circulating growth hormone and insulin-like growth factor 1 (IGF-1) levels, which are central to promoting lean muscle mass, enhancing protein synthesis, and boosting fat metabolism. Researchers observe that CJC-1295 with DAC may help support tissue repair, improve bone density, and modulate metabolism. It does not supply exogenous growth hormone but instead amplifies the body’s own natural pulsatile release, making it a subject of study for muscle development, metabolic balance, and recovery processes.

CJC-1295 DAC Research Details

CJC-1295 with DAC is a GHRH analog engineered with a reactive drug-affinity complex for albumin binding. Literature describes prolonged half-life, sustained GH and IGF-1 elevation in study settings, and use as a model for extended-exposure peptide design.

Purity
99%+ target purity or lot-specific COA value

Sequence / Identity
GHRH analog with drug-affinity complex; verify exact lot sequence by COA

Form
Lyophilized research material unless otherwise specified by COA

Intended Use
Research use only

Research Background

Long-acting GHRH analog containing a drug-affinity complex that binds albumin and extends experimental exposure. Key OneBio research contexts include ghrh receptor research, albumin-binding peptide design, gh/igf-1 axis studies, and pharmacokinetic comparison.

Specifications

Compound	CJC-1295 DAC
SKU / Product	cic-1205-dac
Molecular Weight	~3.6-3.8 kDa peptide range before albumin binding; verify by COA
Formula / Classification	Lot-specific
Database / Identity Note	GHRH analog; verify by COA
Storage	-4°F long-term; 35-46°F short-term refrigerated; 39°F after reconstitution for up to 30 days when appropriate for the research protocol

Quality Verification

Each batch should be reviewed against its Certificate of Analysis, including identity confirmation, purity method, mass/sequence or component confirmation, appearance, and lot-specific handling notes. Blend products should be checked against component-ratio documentation where available.

Laboratory Preparation

Prepare only inside a qualified laboratory using validated solvent choice, concentration, sterility, and storage protocols. For lyophilized peptides, use sterile deionized water or bacteriostatic water when appropriate for the research protocol, mix gently, maintain cold-chain handling, and avoid repeated freeze-thaw cycles.

Product-Specific Q&A

What is CJC-1295 DAC used for in research?

CJC-1295 DAC is used as a research material for ghrh receptor research, albumin-binding peptide design, gh/igf-1 axis studies, and pharmacokinetic comparison. It is not offered for diagnostic, therapeutic, clinical, veterinary, or human-use applications.

What mechanism is most relevant for CJC-1295 DAC?

Long-acting GHRH analog containing a drug-affinity complex that binds albumin and extends experimental exposure.

How should CJC-1295 DAC identity and purity be verified?

Use the lot-specific Certificate of Analysis to confirm identity, purity, mass/sequence or component profile, and any method-specific data such as LC-MS/HPLC. Technical values on this page are research references and should be checked against the delivered lot.

What storage conditions apply to CJC-1295 DAC?

-4°F long-term; 35-46°F short-term refrigerated; 39°F after reconstitution for up to 30 days when appropriate for the research protocol. Keep sealed, dry, protected from light, and avoid repeated freeze-thaw cycles after preparation.

References

PMID 16352683: Prolonged stimulation of growth hormone (GH) and insulin-like growth factor I secretion by CJC-1295, a long-acting analog of GH-releasing hormone, in healthy adults. The Journal of clinical endocrinology and metabolism 2006.
PMID 41490200: Therapeutic Peptides in Orthopaedics: Applications, Challenges, and Future Directions. Journal of the American Academy of Orthopaedic Surgeons. Global research & reviews 2026.
PMID 41476424: Injectable Peptide Therapy: A Primer for Orthopaedic and Sports Medicine Physicians. The American journal of sports medicine 2026.

Research Use Only: For laboratory research and analytical testing only. Not for human or animal consumption, therapeutic use, diagnostic use, food, drugs, or cosmetics.

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Product	Current product
Form	Lyophilized research material unless otherwise stated on the product label.
Purity / Identity	See product listing and available COA/batch documentation.
Storage	Long-term freezer storage around -4°F. Short-term refrigerated storage 35–46°F. Reconstituted materials should be handled under validated laboratory protocols.
Use Standard	Research-use only; not for human or animal administration.

Product Details

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