Product Details
Research-grade peptides with clear specifications, COA-backed quality verification, and Fahrenheit storage guidance for laboratory use.
SS-31 -50MG
Overview
SS-31, also known as elamipretide, is a small, cell-penetrating peptide that specifically targets the inner mitochondrial membrane by binding to a lipid called cardiolipin.
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Description
SS-31, also known as elamipretide, is a small, cell-penetrating peptide that specifically targets the inner mitochondrial membrane by binding to a lipid called cardiolipin. By anchoring to cardiolipin, it stabilizes the mitochondria, which are the powerhouses of the cell. As a result, SS-31 reduces the production of harmful reactive oxygen species (ROS), which can damage DNA and proteins. By improving mitochondrial efficiency, SS-31 boosts cellular energy production, resulting in better ATP generation. This peptide is known to improve the health of tissues that rely heavily on mitochondria, such as cardiac, muscle, and kidney cells. It helps stabilize mitochondrial structure, ensuring they function optimally, which supports overall cellular vitality. Through these effects, SS-31 is thought to enhance energy production, reduce cellular aging, and maintain tissue function, especially in areas vulnerable to oxidative stress.
SS-31 / Elamipretide Research Details
SS-31 (elamipretide) is a cell-permeable aromatic-cationic tetrapeptide. Literature focuses on cardiolipin binding, mitochondrial cristae stabilization, oxidative-stress reduction, and high-energy-tissue models including cardiac, skeletal muscle, renal, and neurologic systems.
99%+ target purity or lot-specific COA value
D-Arg-2,6-dimethylTyr-Lys-Phe-NH2
Lyophilized research material unless otherwise specified by COA
Research use only
Research Background
Mitochondria-targeting tetrapeptide studied for cardiolipin interaction, inner-membrane stabilization, ROS reduction, and ATP/mitochondrial efficiency endpoints. Key OneBio research contexts include mitochondrial assays, cardiolipin-binding research, oxidative-stress models, and atp/respiration studies.
Specifications
| Compound | SS-31 / Elamipretide |
| SKU / Product | 5s-31 |
| Molecular Weight | ~639.8 g/mol |
| Formula / Classification | C32H49N9O5 |
| Database / Identity Note | PubChem CID 7049599 |
| Storage | -4°F long-term; 35-46°F short-term refrigerated; 39°F after reconstitution for up to 30 days when appropriate for the research protocol |
Quality Verification
Each batch should be reviewed against its Certificate of Analysis, including identity confirmation, purity method, mass/sequence or component confirmation, appearance, and lot-specific handling notes. Blend products should be checked against component-ratio documentation where available.
Laboratory Preparation
Prepare only inside a qualified laboratory using validated solvent choice, concentration, sterility, and storage protocols. For lyophilized peptides, use sterile deionized water or bacteriostatic water when appropriate for the research protocol, mix gently, maintain cold-chain handling, and avoid repeated freeze-thaw cycles.
Product-Specific Q&A
What is SS-31 / Elamipretide used for in research?
SS-31 / Elamipretide is used as a research material for mitochondrial assays, cardiolipin-binding research, oxidative-stress models, and atp/respiration studies. It is not offered for diagnostic, therapeutic, clinical, veterinary, or human-use applications.
What mechanism is most relevant for SS-31 / Elamipretide?
Mitochondria-targeting tetrapeptide studied for cardiolipin interaction, inner-membrane stabilization, ROS reduction, and ATP/mitochondrial efficiency endpoints.
How should SS-31 / Elamipretide identity and purity be verified?
Use the lot-specific Certificate of Analysis to confirm identity, purity, mass/sequence or component profile, and any method-specific data such as LC-MS/HPLC. Technical values on this page are research references and should be checked against the delivered lot.
What storage conditions apply to SS-31 / Elamipretide?
-4°F long-term; 35-46°F short-term refrigerated; 39°F after reconstitution for up to 30 days when appropriate for the research protocol. Keep sealed, dry, protected from light, and avoid repeated freeze-thaw cycles after preparation.
References
- PMID 39940712: Elamipretide: A Review of Its Structure, Mechanism of Action, and Therapeutic Potential. International journal of molecular sciences 2025.
- PMID 32554501: Mitochondrial protein interaction landscape of SS-31. Proceedings of the National Academy of Sciences of the United States of America 2020.
- PMID 36400945: Beneficial effects of SS-31 peptide on cardiac mitochondrial dysfunction in tafazzin knockdown mice. Scientific reports 2022.
Expanded Product Information
PeptideTech-style product tools added beneath the existing OneBio product layout: tabs, specifications, COA guidance, shipping/storage information, stock-solution guidance, verification notes, and FAQ.
| Product | Current product |
|---|---|
| Form | Lyophilized research material unless otherwise stated on the product label. |
| Purity / Identity | See product listing and available COA/batch documentation. |
| Storage | Long-term freezer storage around -4°F. Short-term refrigerated storage 35–46°F. Reconstituted materials should be handled under validated laboratory protocols. |
| Use Standard | Research-use only; not for human or animal administration. |
Third-party verification: Review the available Certificate of Analysis and batch documentation before use. Verify identity, purity, appearance, and lot-specific details against your lab requirements.
Are these products for research use only?
Yes. OneBio Research products are sold strictly for laboratory research and analytical testing.
Where do I find storage guidance?
Use the product label, COA, and the storage tab above. Long-term freezer storage is commonly referenced around -4°F; refrigerated short-term storage is 35–46°F.
Can I request documentation?
Yes. Use the COA/documentation request link or contact OneBio Research with the product and lot details.
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