Product Details
Research-grade peptides with clear specifications, COA-backed quality verification, and Fahrenheit storage guidance for laboratory use.
SEMAX -10MG
Overview
Semax is a synthetic heptapeptide derived from a fragment of adrenocorticotropic hormone (ACTH).
$25.00
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Description
Semax is a synthetic heptapeptide derived from a fragment of adrenocorticotropic hormone (ACTH). Unlike ACTH, Semax is modified to cross the blood-brain barrier, allowing it to directly influence the brain. It exerts its effects by increasing brain-derived neurotrophic factor (BDNF), a protein that supports neuron growth, survival, and synaptic plasticity. By boosting BDNF, Semax enhances learning, memory, and adaptability of the brain. In addition, Semax modulates neurotransmitter systems, particularly by increasing dopamine and serotonin levels, which can improve mood, focus, and mental clarity. It also boosts cerebral blood flow, ensuring that more oxygen and nutrients reach brain cells. Furthermore, it supports resilience to stress by stabilizing neuroendocrine responses, promoting calm without sedation. Altogether, Semax acts as a broad-spectrum cognitive enhancer, supporting brain resilience, stress adaptation, and mental agility.
Semax Research Details
Semax is a synthetic ACTH fragment analog with published research in neuroprotection, cognition, ischemia models, BDNF/TrkB expression, and neurotransmitter modulation. OneBio positions Semax strictly for research-use laboratory investigation.
99%+ target purity or lot-specific COA value
Met-Glu-His-Phe-Pro-Gly-Pro
Lyophilized research material unless otherwise specified by COA
Research use only
Research Background
ACTH(4-10)-derived heptapeptide studied for neurotrophic, melanocortin-related, neurotransmitter, and BDNF-linked neurobiology pathways. Key OneBio research contexts include neuroprotection models, bdnf/trkb pathway assays, cognitive-model research, and acth-fragment comparison.
Specifications
| Compound | Semax |
| SKU / Product | semax |
| Molecular Weight | ~813.9 g/mol |
| Formula / Classification | C37H51N9O10S |
| Database / Identity Note | PubChem CID 9811102 |
| Storage | -4°F long-term; 35-46°F short-term refrigerated; 39°F after reconstitution for up to 30 days when appropriate for the research protocol |
Quality Verification
Each batch should be reviewed against its Certificate of Analysis, including identity confirmation, purity method, mass/sequence or component confirmation, appearance, and lot-specific handling notes. Blend products should be checked against component-ratio documentation where available.
Laboratory Preparation
Prepare only inside a qualified laboratory using validated solvent choice, concentration, sterility, and storage protocols. For lyophilized peptides, use sterile deionized water or bacteriostatic water when appropriate for the research protocol, mix gently, maintain cold-chain handling, and avoid repeated freeze-thaw cycles.
Product-Specific Q&A
What is Semax used for in research?
Semax is used as a research material for neuroprotection models, bdnf/trkb pathway assays, cognitive-model research, and acth-fragment comparison. It is not offered for diagnostic, therapeutic, clinical, veterinary, or human-use applications.
What mechanism is most relevant for Semax?
ACTH(4-10)-derived heptapeptide studied for neurotrophic, melanocortin-related, neurotransmitter, and BDNF-linked neurobiology pathways.
How should Semax identity and purity be verified?
Use the lot-specific Certificate of Analysis to confirm identity, purity, mass/sequence or component profile, and any method-specific data such as LC-MS/HPLC. Technical values on this page are research references and should be checked against the delivered lot.
What storage conditions apply to Semax?
-4°F long-term; 35-46°F short-term refrigerated; 39°F after reconstitution for up to 30 days when appropriate for the research protocol. Keep sealed, dry, protected from light, and avoid repeated freeze-thaw cycles after preparation.
References
- PMID 41004910: Modulation of neuropathological pathways by bioactive peptides and proteins/polypeptides: Targeting oxidative stress in neurodegenerative diseases. Neuropeptides 2025.
- PMID 29798983: [The efficacy of semax in the tretament of patients at different stages of ischemic stroke]. Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova 2018.
- PMID 16635254: Semax, an analogue of adrenocorticotropin (4-10), binds specifically and increases levels of brain-derived neurotrophic factor protein in rat basal forebrain. Journal of neurochemistry 2006.
Expanded Product Information
PeptideTech-style product tools added beneath the existing OneBio product layout: tabs, specifications, COA guidance, shipping/storage information, stock-solution guidance, verification notes, and FAQ.
| Product | Current product |
|---|---|
| Form | Lyophilized research material unless otherwise stated on the product label. |
| Purity / Identity | See product listing and available COA/batch documentation. |
| Storage | Long-term freezer storage around -4°F. Short-term refrigerated storage 35–46°F. Reconstituted materials should be handled under validated laboratory protocols. |
| Use Standard | Research-use only; not for human or animal administration. |
Third-party verification: Review the available Certificate of Analysis and batch documentation before use. Verify identity, purity, appearance, and lot-specific details against your lab requirements.
Are these products for research use only?
Yes. OneBio Research products are sold strictly for laboratory research and analytical testing.
Where do I find storage guidance?
Use the product label, COA, and the storage tab above. Long-term freezer storage is commonly referenced around -4°F; refrigerated short-term storage is 35–46°F.
Can I request documentation?
Yes. Use the COA/documentation request link or contact OneBio Research with the product and lot details.
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