Description
Selank is a synthetic peptide derived from tuftsin, known for its neuroprotective and anxiolytic properties. It acts on the central nervous system by modulating neurotransmitters, such as enhancing GABAergic activity and balancing serotonin and dopamine levels. In animal studies, Selank has been shown to reduce anxiety, improve learning and memory, and support stress resilience. These effects make it a candidate for managing anxiety and cognitive function, though most research is still preclinical.
Selank Research Details
Selank is a synthetic analog related to the endogenous tetrapeptide tuftsin. Published experimental work discusses effects on stress-response behavior, neurotransmitter-system regulation, gene-expression patterns, and immune-neural signaling. OneBio positions Selank strictly as a research material for controlled laboratory investigation of peptide neurobiology.
99%+ target purity or lot-specific COA value
Thr-Lys-Pro-Arg-Pro-Gly-Pro
Lyophilized research material unless otherwise specified by COA
Research use only
Research Background
Synthetic tuftsin-family heptapeptide studied for neuromodulatory, anxiolytic-like, and neuroimmune signaling effects in experimental systems. Key OneBio research contexts include neurobiology research, stress-response models, peptide stability studies, and neuroimmune signaling assays.
Specifications
| Compound | Selank |
| SKU / Product | selank-30mg |
| Molecular Weight | ~751.9 g/mol |
| Formula / Classification | C33H57N11O9 |
| Database / Identity Note | PubChem CID 11957369 |
| Storage | -4°F long-term; 35-46°F short-term refrigerated; 39°F after reconstitution for up to 30 days when appropriate for the research protocol |
Quality Verification
Each batch should be reviewed against its Certificate of Analysis, including identity confirmation, purity method, mass/sequence or component confirmation, appearance, and lot-specific handling notes. Blend products should be checked against component-ratio documentation where available.
Laboratory Preparation
Prepare only inside a qualified laboratory using validated solvent choice, concentration, sterility, and storage protocols. For lyophilized peptides, use sterile deionized water or bacteriostatic water when appropriate for the research protocol, mix gently, maintain cold-chain handling, and avoid repeated freeze-thaw cycles.
Product-Specific Q&A
What is Selank used for in research?
Selank is used as a research material for neurobiology research, stress-response models, peptide stability studies, and neuroimmune signaling assays. It is not offered for diagnostic, therapeutic, clinical, veterinary, or human-use applications.
What mechanism is most relevant for Selank?
Synthetic tuftsin-family heptapeptide studied for neuromodulatory, anxiolytic-like, and neuroimmune signaling effects in experimental systems.
How should Selank identity and purity be verified?
Use the lot-specific Certificate of Analysis to confirm identity, purity, mass/sequence or component profile, and any method-specific data such as LC-MS/HPLC. Technical values on this page are research references and should be checked against the delivered lot.
What storage conditions apply to Selank?
-4°F long-term; 35-46°F short-term refrigerated; 39°F after reconstitution for up to 30 days when appropriate for the research protocol. Keep sealed, dry, protected from light, and avoid repeated freeze-thaw cycles after preparation.
References
- PMID 36322304: Selank, a Peptide Analog of Tuftsin, Attenuates Aversive Signs of Morphine Withdrawal in Rats. Bulletin of experimental biology and medicine 2022.
- PMID 41490200: Therapeutic Peptides in Orthopaedics: Applications, Challenges, and Future Directions. Journal of the American Academy of Orthopaedic Surgeons. Global research & reviews 2026.
- PMID 31243679: Effect of Selank on Morphological Parameters of Rat Liver in Chronic Foot-Shock Stress. Bulletin of experimental biology and medicine 2019.

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